Hmmm... I'd say 90% of the time, I still use solely DVDShrink (which automagically calls the Nero Burning ROM). That's pretty simple. I've checked out AnyDVD and CloneDVD2, but does it do compression as good as DVDShrink? DVDShrink still does a very fine job compressing a DVD-9 disc into a DVD-5 disc...especially when you choose the "Perform deep analysis" and "compress video with high quality adaptive error compensation" options.
The times when DVDShrink doesn't work, due to ARccOS or other reasons, I might use DVDDecrypter. Just for fun, I'll use VOBBlanker to remove some of the unwanted data and then MenuShink (awesome program) to compress the menu down to still frames. Frequently, I can compress a DVD-9 disc down to DVD-5 without lowering the main movie quality by simply trimming out all the non-feature-film extras.
Complicated? Not really. It's a hobby and it's fun for me.