Yes, Nero works fine for PAL to NTSC. I bought a boxed set of Region 2 DVDs when visiting Ireland a few years back because they didn’t have the series on Region 1 format, and managed to port the entire thing to NTSC without any problem. I have a 25 inch standard definition TV and you can’t tell the difference on a screen that size.
If I was burning a DVD to keep for the ages I might feel differently, but until I buy that 60 inch high definition television, my tired old eyes will never notice. The only drawback to the Nero procedure is the length of time it takes to do the transcoding and ConvertX is not much better. I only wish DVDFab could both transcode and strip region protection in one step.
Why the heck do DVD publishers region code their media if they have no intention of distributing the content elsewhere? I can understand the PAL formatting because that is what Europeans need, or region coding something intended for global release, but why make is so complicated to get a Region 1 NTSC disc if the series is not likely to be seen elsewhere?