If you have the plextor premium then use v5. I couldn't make a backup properly with v4 (except for a play only disc) but with v5 it installs and play perfectly. What I do is, use Alcohol and read image with Securom *NEW (v4.x/v5.x) setting with read speed at 4x for image and 1x or 4x for DPM.
Now use the latest version of the BWA Builder and load the mds file that Alcohol created and then click on File then Clean Last Loaded Curve. Then save it as a BWA file.
Load up the BlindWrite Tweaker and have the following settings:
Basic Settings Tab:
Start Page = Write
Uncheck all 4 settings on the left (turn decrypt on to don't split image, this is the latest Tweaker btw).
Max Read Speed = 4x (some I list here are not for the actual burn but you could just use bw v5 with these settings for reading too!)
Write Speed CD = 4x
Handle Read Error = Automatic
Subcodes For Data = Automatic
Subcodes For Audio = Automatic
Check Write with Plextor Premium
Topology Method = Automatic
Read Topology = Automatic
Extraction Speed = 4x
Now click on BROWSE and select the BWA file you just recently created.
Advanced Settings Tab:
Click on BROWSE and select the Alcohol image, then click on Run Blindwrite and Blindwrite will load up. Just click on WRITE in Blindwrite and you get a working copy that will work for installing and playing with.
These settings are ONLY for using a Plextor Premium as the burner. Those are what I use and I get a working copy everytime. I can even reread the copy and make another one that works.
EDIT: Also forgot to say that BlindWrite v5 ONLY uses Variwrite, v4 does not. Thats why you need to use v5.