Nope, don't need to run DVD Decrypter and AnyDVD at the same time. If you use DVD Decrypter, then you must use another program like CloneDVD to remove the unwanted stuffs and compress the data to fit in one DVD-5 disc. CloneDVD can also split the movie to two DVD-5 discs, to maintain the original picture resolution. The final step is to burn the data from the hard drive to the DVD with CloneDVD.
If you use AnyDVD, then you don't have to copy the whole movie to the hard drive, and then reshrink it. Just edit the movie using CloneDVD, then burn the data to the hard drive.
Don't have hands-on experience with Copy2DVD.