Ouch, Primary IDE. Usually if it’s the Secondary IDE channel in PIO Mode, uninstalling it and letting Windows re-detect it shouldn’t be a problem.
In the past, I’ve uninstalled my own Primary IDE channel in Device Manager (right-click -> Uninstall) with no ill-effects (Windows just re-detects it after a reboot, and puts it into DMA Mode).
However, if your OS (Windows) drive is on your Primary IDE channel, do this at your own risk. As I say, I didn’t have a problem, but you never know.
You might want to wait and see if someone can help you run the .vbs file (have you tried right-clicking on it and opening it that way?)