Don't expect to be able to burn at 20x in an external enclosure without slowdowns. It might be possible, but don't expect it. Using FireWire will improve the odds.
The drive is not born with region free firmware (no drive is these days), so you'll have to use unofficial firmware.
If you're using the drive in the external enclosure, I think there's already a short 80-wire IDE cable in the enclosure - I've never seen an enclosure that didn't come with an internal IDE cable.