Hello and welcome to the forum.
If you are playing from a burner you must hide the CD-R/W ATIP using Ignore Media Type from the Tray Icon emulation options. Alcohol must be installed on this machine to do this. Alternatively, you can emu with Daemon Tools or CloneCD.
Playing from a CD/DVD-ROM does not matter.
If the backup does not run, try Bad Sectors emu. If it then works then the backup is not as it should be from a Litey 52x; although this burner is known to be hit or miss. Shoulda got an ASUS