Region on dvd

I was not sure which section to post this in as a “newbie” but I’m sure the admins will direct it to the correct location. I have DVDCopy 2 platinum and AnyDVD 3.6.1.1.
I have been getting discs from a online dvd rental service and copying them just fine however recently I got a Simpsons dvd and it plays fine in my player but when I copy it and put it in plyaer it says "this disc is not formatted for this region.
I have the default region set to United states and Canada and all of the feature removal options checked.
Does anybody have any ideas to try to get this one copied cause i’ve already wasted a couple of dvd’s.