OK, Transfer Mode is set to DMA if available, but what is Current Transfer Mode?
It still can be PIO, which is bad. After CD/DVD reading problems Windows will change Transfer Mode to next lower and try to read again, and change again if still there is a problem, ..., until it's set to PIO (it's last one, and worst).
If Current Transfer Mode is NOT Ultra DMA Mode X, uninstall IDE Channel where the device is and rebot PC. Windows will reinstall it.
If you have DVD on the same IDE channel where is HDD with OS, then find tool to force DMA for IDE channel/device. But it's recommended to install DVD device to another channel.