Hey RogerRog--I want to add my two cents here. I am a PX-716SA owner--my drive is installed in a Dell Dimension XPS Gen 3 system. My system uses an OEM Intel 925X motherboard with 4 SATA ports--almost identical to the OEM Intel 925XE motherboard used by the current Dimension XPS Gen 4. Like others have told you correctly, any Dell system with built-in SATA will work with the PX-716SA, because all Dell systems with SATA motherboards and all Dell systems for that matter use Intel boards with Intel chipsets. And any Intel board with an Intel Xpress (915,925, etc) chipset will work with the PX-716SA. Here is what you must do: after you install the drive, go into your BIOS setup, and make sure the SATA port you hooked up the 716SA to is enabled--if it isn't, enable it! My Dimension XPS Gen 3 required me to enable the port in the BIOS setup after installing the drive. Next issue: AHCI mode. My Dimension XPS Gen 3 came with the SATA controller in AHCI mode, and the SATA controller using Intel drivers (Intel Application Accelerator/Matrox Storage Driver). The PX-716SA drive works fine in AHCI mode, however, on my Dimension XPS Gen 3 system, incompatibility problems occur because of AHCI mode and the Intel driver required for it. The incompatibility is a blue screen of death error (STOP 0X00008086) caused by some programs (i.e. pxscan) that depend on ASPI--these programs appear to cause the Intel driver to treat the 716SA as a hard drive, and hence the blue screen error. To avoid this problem, don't use these programs (pxscan and Kprobe--Kprobe is used by some users like myself who have a Liteon drive in the same system), or reinstall Windows XP and all of your drivers and software after switching the SATA controller to ATA mode in the system BIOS. Switching this controller to ATA mode allows Windows XP to use standard Microsoft drivers with the SATA controller--doing so solves the blue screen/incompatibility problem because the Intel SATA driver is no longer used and the SATA controller emulates a regular IDE controller so compatibility is no longer an issue.