The exact same problem with me!!!
I've juste changed drives 3 times(lite on 48/24/48, 2x lite on 52/24/52) et had that problem each time after 15 min of use!
I thought first I was really unlucky but it seems that luck has nothing to do now and I absolutely don't know what could cause that!? any harware (software) bad behaviour?
I'm working under : windows xp pro sp1
mb: asus a7n8x deluxe
proc: athlon xp 2600+
ddr apacer 1go 333
dvd toshiba 1712
Any idea is welcome,