Laser Calibration is pretty useless:
Perform Laser Power Calibration - If this box is checked, an optimum laser power calibration will be performed before the write operation is started. Usually the writer will do this automatically. This option is useful, if you wish to check, if the inserted media is capable of the selected write speed (e.g., 12x speed on uncertified media). The calibration will not be done, if an erasable Media is inserted, or Write Simulation is enabled.
The Zip650 can indeed do a perfect backup of SafeDisc 2 and therefore B&W is no problem. I'm working on a complete SafeDisc 2 list so if anyone has info on this, please mail me at firstname.lastname@example.org