There appear to be some things that won't work in Vista, probably because of restrictions from the UAC or whatever protections are involved. I am not currently running it in Vista, so I can't confirm your observations myself.
ImageDrive is not available, I can't get InfoTools to run, logs don't show DMA status for your drives, and it appears the buttons in CD/DVD speed are missing. I don't know if they are working on it, or whether it will ever work. You might pass it along to Nero and see what they say.