The CloneCD 'issue' relates to the Virtual Drive that was shipped with V220.127.116.11 and the CCDTray that runs in the SysTray. If the virtual drive is installed - even if it is disabled - then any game protected by SafeDisk 2.90.040 [which Devastation is] will fail the CD Check. Same is true for the CCDTray. You will need to exit the tray program before running the game.
The CCDTray is only useful for playing a backup of the game in a Burner or for launching CloneCD from the SysTray, so as long as you have the original in the burner or a backup in a CD-ROM or DVD-ROM drive you don't need it. Trouble will be when you have a pirate copy and only a single burning optical drive........
Or change the command line in Properties of the icon to show udb.exe instead of devastation.exe