There is a tool named CDemu, which currently handles cue+bin files. On the webpage you read
Looking ahead: CDemu was first created to support bin/cue images. Ideally, we'd like to be able to support Nero (.nrg), Disc Juggler (.cdi), Clone CD (.ccd), etc... Anyone with spare time and spare patches would be appreciated
so maybe in the future it will be possible with .NRG too.
(BTW: I noticed a nice, and unintentional, double-meaning in the words: looking ahead! )