You'll usually need to F-disc first....
frankly, I'd clone/ghost your current boot drive to a small partition
on your new HDD, REMEMBER to defrag the drive first!
but leave the current drive as the boot drive.
but make it a point to relocate all data from that drive
I'd recommend running Ghost your boot drive to copy it to your "backup" atleast once a week, but rescheduel your backup
so that when you add anything new you are adding it to a system that you have JUST backed up.
That way when an installation "goes wrong" you don't lose everything.
Then when your boot drive eventually dies all you'll need to do is go into startup and change the boot device to "restore" your system.
I use a small (15Gb) drive as my boot drive and my boot setup is
copied/cloned/ghosted to a 6.4Gb drive weekly.
I actually have TWO of those 6.4's and I alternate which one I
make my backup to, so even if the operation somehow "Fails" I have an undisturbed backup that's two weeks old.
My entire boot setup (including 12 years of archived e-mail)
only takes 5.6Gb and one of those 6.4Gb drives is only
connected for my routine sunday afternoon backup operation.
(my 40Gb "E" drive is in a removeable drive tray)
THE question people fail to ask is "Am I paranoid ENOUGH about protecting my system setup and data?"
HDD failures are something everyone should expect, bt there is no predicting when they will arrive.
If you operate your computer expecting your HDD to fail in the next 7 days you won't ever lose all that much.