With knowledge of many systems failing to do at least an upgrade from earlier versions of Windows because of various antivirus solutions, I can understand why third party antivirus solutions gets disabled as part of the process, good go M$.
With that said and while I do have 'some' to say about Kaspersky's own methods, they are correct here... It is mandatory for Microsoft to make the store 'the' place to be to compete with Apple and Google and so yes, they really try to tax third parties (isn't that part of what any store is about?) by forcing developers to adopt to the new regime... That is what Universal Windows Platform (UWP) is about.
So why not Microsoft as well as Apple and Google?
One of the very few things that is really great about Windows is the diversity of the software available, where the vast majority is still based on common PE/PE+ format which is native and available for download on many sites. UWP does not change 'that' much apart from partly more forced design and being installed from a store unless developer's extentions are turned on (you can probably imagine how many users will) and so yes... Kaspersky is right.
Now, Microsoft really are in the hands of the users here and luckily we will be the ones who together will decide how it goes. If we choose to use it, it will be a success sacrificing diversity for convenience as for many small developers and freewares, the store will be 'off limit' (they would kill off access standard PE/PE+ executables today if they could to get to that level of control). Would we want it to happen?
As for Microsoft's own antivirus implementation in Windows 10? Nah... I have too many unpackers and other 'suspicious' programs on my computer to use that. Simply way too little user control for that to happen, but generally the era of antivirus is over. They slept when the world turned and today, ransomware and other types of infections managing to evade detection by your traditional antivirus calls for solutions covering several types and layers of detection, something that is, so far, not part of one single package. To avoid what could be seen as advertising, I will not elaborate any further on the subject