Try using AnyDVD HD to rip and create the ISO on the hard drive. Then mount the image in Slysoft’s free virtual drive program, VirtualClone Drive. http://www.slysoft.com/en/virtual-clonedrive.html
See if that helps.
I don’t have any problems, but I use the last version of PowerDVD 7 that still supported playback from files, and refuse to “upgrade”. Using AnyDVD in the background, I haven’t had to so far.