I'm assuming that it is a internal SATA drive (those are the ones I'm familiar with). If that is the case, install the drive into the enclosure. Plug it into your computer via the USB (or firewire). If you are using Windows XP, it should recognize the drive without having to install drivers (again assuming that you have SATA controllers on your motherboard). You will then need to initialize the drive and partition it. You do this under device manager and disc management. Once the partitioning is done, you are good to go.