From what I recall reading at the their web site it is not always going to work. There will be some that are problems and will be problems.
How does the slide card compare to other backup solutions you might ask? The answer to that question is, that it works as well as every swap modchip on the market, if not better. The slide card biggest advantage, is that it leaves the PlayStation2 console 100% intact. There is no modchip to steal power from the laserlens, so the system is completely "stress" free. No other backup solution on the market can say that.
We are not gonna lie.. Bigger modchips like Messiah, Magic and DMS3 performs better in some ways, and you do not have to use a swap disc to get the games started. But these chips installs with more than 20 wires, can be detected by many new games, and is a bit more expensive, and you have to be an expert to install them. They make big modifications to the internal system that is not good in the long run. These chips are very compatible with backups of all kinds, no matter how they are burned, what there toc. sizes are etc.
The alternative modchips like No Solder, NEO 2.2, S-BOX NEOKey, the Flip-Top Cover and the Slide-Card are a little more sensitive on that account. You might experience a game than runs fine on a Messiah or Magic chip, but it simply will not run with the slide card. Bad luck.. You may trye burning in some other way - but generally we say that: If a Messiah, Magic & DMS3 chip performs a 100% - a swap solution like No Solder, NEO 2.2, S-BOX NEOKey and Slide-Card performs around 90%. Simply forget the 10% of games you can't backup and play, and be happy having a backup solution that do not void the Sony warranty, that does not stress your laserlens, that is totally secure and very easy to use.