Has any one sucssesfuly copied safedisc 18.104.22.168 games and got them to work?
Many people. However the ability to do so is hardware dependent. You might also like to read the sticky thread on this subject.
A good and from my experience reliable method is creating a mini image. Although it's not a 'physical backup' I never got any problems using Alcohol's/DTool's vdrives and it works a like charme up to latest SafeDisc versions.