What about the "plus" variety?
The only thing I have changed is the addition of a Tascam 2000 audio interface, along with Cubase LE4 software.
Have you already try to restor your system to a time before these changes?
Note: I downloaded Driver Boost to scan for outdated drivers. Its scan showed that the Intel(R) ICH9M/M-E Family 4 Port SATA AHCI Controller 2929 was out of date, but when I went through Device Manager it stated that the driver WAS up to date.
These driver scanners are usually useless. Some can even be considered as malware.
Apart from that, your drive is USB connected, so the drivers for internal storage controllers don't matter.
I have no idea what to do next. Any help and suggestions are greatly appreciated.
Have you already tried the drive with another computer? What happens if you are using DVD writing software?