External USB hard Drive tabl;e change



I have 2 USB external hard drives 1 x 160 GB and 1 x 250 GB these are FAT 32 and both have data on them to 75% of capacity approx., is it possible to safely change these from FAT 32 to NTFS with Partition Magic or some other software without formatting these drives completely.
Any serious problems in doing this expected after ?


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