Just looking over your thread so I experimented a bit. Like Tanweer, I had no problems. All files open in fab, etc., etc.
Which version are you using?
Recent version(s) had issues (crashes, failures) when attempting to open previously ripped files on the hdd.
Ripped Davinci Code, platinum v.184.108.40.206, main movie, target size dvd5 (4300 MB)
file size = 4,483,782,656 bytes.
Then re-ripped to .ISO (Full Disc mode)
file size = 4,484,880,384 bytes.
Then burned to +RW disc (Full Disc mode)
file size = 4,295,147,520
steps #2, #3
Video_TS original rip to f: hdd