I have a very similar problem to Simon and his Quake 4 issue the other month.
I have just purchased Microsoft Office Enterprise 2007 and my dvd drive is not reading the disk at all. It makes noises but does not read the disk. (Have installed many other apps from DVD ROM, but this brand new disk will not read.)
I have the following drive - ATAPI DVD DH18A1P dvd player
My system Intel Core2Duo E6640 Dual Core CPU, 2x 1GB KINGSTON PC5300 667Mhz DDR2 RAM, 400 GB HDD SATA2 HDD, 18x DVD +/- RW Optical Drive, PCI X 8800GTS 640MB Graphics
Someone has said it may be something to do with copy protection
It is an original dvd disk
Any help please