DVD locks drive

I’ve got a rented copy of Tim Burton’s Corpse Bride. It plays just fine on my DVD player, but I’ve tried it in three different computers and each behaves the same way - as soon as the DVD is inserted into a drive, anything that needs that drive stops working, so you can’t even run explorer to see the disk contents and you can’t scan the disk. Does this sound like a copy protection or do I just have a rogue disk?

I had no problem watching and exploring it on a MadDog Triple Format External. (NEC 4550)

Might be the disk.