Thanks for the suggestion, I had not tried that, sadly it didn't work. I have also tried uninstalling the K lite codec pack as that is the only similarity I can think of between the 2 machines I used but that also didn't work.
I have made a recording of the sound I am getting - this is dragonforce (a really loud recording) on max volume and with my speakers up to maximum.
Here is a photo of the back of the card:
XfiTitanium.zip (35.7 KB)