Compress an ISO?

I have an iso i made from one of my games and i mount it on a virtual drive but i was wondering if it was possible to compress an iso so i could fit it onto a little flash drive of mine so it wouldnt take up the space on my hard drive

Not sure how “little” your flash drive is, but you can compress an ISO. Here is a link to a tutorial to compress using MagicISO:

i have a 2 gb flash drive. using magiciso can i still mount the disc as a virtual drive after i compress it?