Most original movie dvds are to big to do a 1:1.
CloneDVD can make an image (ISO) from a bunch of files on your hdd, Im not sure if it can read directly off a dvdrom to an image in the same 'sector by sector' method used in CloneDVD.
Even then, it can only read from an unprotected disc.
To make the most of CloneDVD, you'll need a ripping tool to decrypt the files on the dvd first.
Might I suggest DVD Decrypter