Why don't you try to uninstall CloneDVD, make sure the Elaborate Bytes directory is deleted, then re-install it.
Quite frankly I don't think that will help, but no harm in trying. Sounds like you've got some software running that prevents CloneDVD for accessing the drive.
You can also try disabling all startup programs.
Go to start-run, then type in- msconfig
Click on the startup tab- then disable all- then reboot.
Now try CloneDVD again, if it works, go back to the startup tab and enable one at a time to isolate the software that is causing the conflict.
XP needs nothing in the startup tab to function properly.