Can CloneCD burn safedisc2.5+?
Yes but you may (probably will) have difficulties in making copies of sd 2.8+ with ccd that will work on systems that don't have ccd installed with hide cdr media activated.
So you dont need any special cd drives to burn games of 2.5-2.8 safedisc?
Yes, you will need a 2 Sheep Burner.
If you don't give a rat's bum about emulation, use CloneCD and whatever burner you have.