SoftICE is a program that is indeed used for cracking all kinds of software. When running a program, you might be asked for a code, serial number or whatsoever. With SoftICE, you can record the position where the program is running, decompile the program and crack it (well it sounds 1000x easier than it is).
Some programs/protections check if SoftICE is running, in order to make sure nobody's trying to crack. If you get this message when there's no SoftICE installed, I presume that there's another program attempting to scan the software you are running. Maybe you can check it that, by closing all progams running in the background!