Games are a tricky bunch. There are several advanced copy guards on the disks, some of which can only be backed up with certain software (there is no one software for every game), some of which can only be backed up on certain drives, in generall, there will be a specific method to backup each game.
I don't back up a lot of games but here is what you are probably going to have to do. Use various programs and identify the specific copy protection on your game. Find specific methods to deal with that particular copy protection. Follow those methods. In many cases, there will be a spelled out proceedure for that particular game (here or elsewhere).
As has been stated, this thread will probably be moved, but in the mean time...
here is a list of games and what copy protections they have. If your game is not listed, after you learn how to break it, consider adding it to this list to help others.
here are the programs that can scan your disk and identify the copy protection
Not to put this site down (after all it is my home), but with games, sometimes it helps to search a few sites for the title of the game. Search here but afterdawn is another good site with lots of info on game copy protection. Somewhere or other there will be a specific way to do that particular game.
Hope that helps.
Fyi this is the main copy protection forum here, where this kind of thing is discussed to extent (and where your thread might get moved as it belongs there).