'Scuse me for butting in regarding a subject that I know very little about (I use DVD for data, and have made only 3 DVD Videos in my time), but I think the original poster was asking whether he can make a DVD Video with Plextools, not Nero.
I can confirm to Valeron that in making DVD Videos I did indeed (perhaps naively) just write the VIDEO_TS and AUDIO_TS directories (that had been created by DVDShrink) to a DVD+R via Plextools' DVD-ROM maker (with bitsetting on). The resulting discs play back fine in my cheap DVD Player.
Have I just been lucky? Should this not have worked?