I have done all episodes with Instantcopy. I did not like the quality of DVD2One on them. Some of the disks are up to 7gigs. Not ideal for DVD2One.
Here are my notes. I can't be certain about all the numbers anymore. I remove ALL the subtitles and leave DTS and DD5.1 soundtrack. Only those two sounds tracks.
Disk6 takes more work.
These number give you an output between 4.33gigs and 4.36gigs.
I hope that helps. It at least gives you a starting point