If this happens, something is broken on your computer. If you have Sonic DLA or Nero InCD installed, this is a good opportunity to get rid of it.
My vote is for AnyDVD for many reasons. The "PC-Friendly" removal of DVD-Region + CSS Free is a joke - it simply disables AutoInsert notification and messes up AutoPlay. Haha, I could have done this myself.
AnyDVD works as a driver for the whole system, DVDR+CSSFree works in user mode invading the process space of the running application.
Both has its advantage and disadvantage.