Software Problem: problem with dvd fab

Been using fab for two years now and never had this problem. Just purchased Desperate Housewives season 4 ,was using 5.8.3.0 .First three disks were no problem but the fourth would never get past open dvd source when i cancled it locked up and i had to do a hard boot.tried it with pathplayer off and it did the same thing , also tried it with the last verison of 4.0 and same result. Upgraded to 5.0.9.0 same result . It only does it with this disk and the funny thing is i tried it on 5.0.3.8 that i have on my other computer and it worked fine. Have done 4 movies sense with no problems. Would do a clean install but it's the only disk i've had problems with in a long time. I've been using the same computer for 3 years and i have made no changes to it . Any suggestions would be appreceated. Thank you.